Inflammation and cancer are closely related and favor each other mutually. We are aiming to find the connection between pancreatic cancer and arachidonic cascade, in which we knocked out the key metabolite 15pgdh in mice and established an inflammatory syngeneic mouse model. Regarding the following steps, we are focusing on evaluating the fibrosis level and vascularization in pancreas under an inflammation-enhanced condition, in which imaging techniques such as microCT are expected to provide supportive data.