The sustainability of structural design and construction is attracting the attention of researchers and engineers, as well as structural safety performance. The research unit aims to the two key research themes, i.e., (1) safety analysis and optimization of structures under extreme loads (e.g., post- earthquake fire, long-period ground motion (LPGM), and near-fault ground motion (NFGM)), including the application of high-performance materials, and (2) recycling of wastes arising from the extreme loads and strengthening of the structures after subjected to the extreme loads. The two themes also can be shortly called Design for Safety and Sustainability (DfS²). The research activities will be conducted using advanced numerical methods (FEM and DEM), algebraic analysis, and experimental verification, to develop technology to promote the Next-generation design of structures. The main research topics that research units would like to conduct are the safety of concrete structures, structural analysis and optimization, Fiber-reinforced polymer (FRP)-repaired structures, and resilient structures, and evaluation and optimization of the structures with Design for deconstruction, and optimization of eco concrete such as volcanic ash concrete, development and application of high-performance materials (Textile reinforced cementitious composite, structural health monitor cementitious composite, nanotechnology for construction), and sustainable structural design, etc.