RESEARCH

Research Units

Quantification of Three Dimensional Vascular Network

Blood vessels change their morphology according to various physiological and pathophysiological conditions. In the field of vascular biology, many biological mechanisms are hypothesized, however, it is very difficult task to quantify the three dimensional vascular architecture.
Our collaboration has already established the image processing method of vascular network (Arima et al., Journal of American Heart Association, 2018). The aim of our team is to establish the unique quantification method of three dimensional data.

Figure: 3D image of murine bone and vascular network in lower leg.

Quantification of Three Dimensional Vascular Network

Unit members

  • Japan
    Yuichiro ARIMA
    Assistant Professor, International Research Center for Medical Sciences (IRCMS), Kumamoto University/X-Earth Center, Faculty of Engineering, Kumamoto University
    Japan
  • Japan
    Unit coordinator
    Toshifumi MUKUNOKI
    Professor, Faculty of Advanced Science and Technology, Kumamoto University/X-Earth Center, Faculty of Engineering, Kumamoto University
    Japan
  • Japan
    Jun OTANI
    Professor, Faculty of Advanced Science and Technology, Kumamoto University/X-Earth Center, Faculty of Engineering, Kumamoto University
    Japan
  • New Zealand
    Patrice DELMAS Website
    Associate Professor, Department of Computer Science, The University of Auckland /IROAST Visiting Professor
    New Zealand

Achievements

Publications

Arima Y, Mukunoki T, et. al., Sample Preparation for Computed Tomography-based Three-dimensional Visualization of Murine Hind-limb Vessels. J Vis Exp. 2021

Grants

(Application)

Grants-in-Aid for Scientific Research-KAKENHI- Challenging research 2022, “CT-based immunostaining”

Activities

Presentation

  Yuichiro Arima, “Visualization of blood vessel microstructure by CT ~Efforts of medical-engineering collaboration~”, The 8th International Workshop on X-Ray CT Visualization for Socio-Cultural Engineering and Environmental Materials, 2021.

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