RESEARCH

Research Clusters

Nano-medicine and Drug Delivery System

Introduction of gene or drug into cells has been used for a wide range of medical applications. We are studying the use of physical delivery of drug or reprogramming factors into the cells and tissue, as a safe and reliable method. We are also exploring integrated diagnostic and therapeutic (theranostics) modalities/nanoparticles/agents, as a unique approach in nanomedicine.

Physical deliveries are based on applying electrical/mechanical stresses to the cells. In this respect, attention has been made to understand biophysical reactions to reversibly manipulate the cells by the external stress. We have been investigating promising physical delivery methods including: electroporation with nanosecond pulsed electric fields, needle-free painless microinjection, micro/nano-particle carrier laser-biolistic delivery, sonoporation with microfluidics, and shock waves; which are shown to be appropriate for clinical applications.

Nano-medicine and Drug Delivery System

Cluster members

  • Japan
    Coordinator
    Hamid HOSANO Website

    Professor
    Institute of Industrial Nanomaterials, Kumamoto University

    Japan
  • Japan
    Nushin HOSANO

    Visiting Asscociate Professor
    Institute of Industrial Nanomaterials, Kumamoto University

    Japan
  • UK
    Konstantinos KONTIS Website

    Professor
    School of Engineering, University of Glasgow

    UK
  • Australia
    Firuz ZARE Website

    Professor; Head of School Electrical Engineering and Robotics
    University of Queensland of Technology

    Australia
  • India
    Viren Ivor MENEZES Website

    Professor
    Department of Aerospace Engineering, Indian Institute of Technology Bombay

    India
  • USA
    Hamid GHANDEHARI Website

    Professor/Chair of Department/Director of Utah Center for Nanomedicine
    Department of Molecular Pharmaceutics, University of Utah

    USA
  • USA
    Amir A. FARAJIAN Website

    Professor
    Department of Mechanical and Materials Engineering, Wright State University

    USA
  • Netherlands
    Pouyan BOUKANY

    Associate Professor
    Department of Chemical Engineering, Faculty of Applied Sciences, Delft University of Technology

    Netherlands
  • UK
    Stelios RIGOPOULOS

    Reader
    Department of Mechanical Engineering, Imperial College London

    UK

Achievement

Publications
2023
Publications

Ziqu Cao, Konstantinos Kontis, Hamid Hosano, Craig White, Ting-Tsung Chang, Muhammed Burak Agir
Vortex Ring Formation Following Shock Wave Diffraction in Low-Pressure Environments Flow,
Turbulence and Combustion, 111(4) 1127-1138, 2023
DOI: https://doi.org/10.1007/s10494-023-00486-3

Md. Mijanur Rahman, Nushin Hosano, Hamid Hosano,
Recovering Microalgal Bioresources: A Review of Cell Disruption Methods and Extraction Technologies
Molecules, 27(9) 2786-2817, 2022
https://doi.org/10.3390/molecules27092786

Grants

Grants-in-Aid for Scientific Research, Kakenhi (B), 2021-2025

Activities

Awards

The Carlsberg Foundation “Senior Researcher Award” August 2022 (World Congress on Electroporation), Hamid Hosano

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