STAFF

Director

  • Takashi HIYAMA
    Dr. Takashi HIYAMA

    Distinguished Professor
    Priority Organization for Innovation & Excellence

Vice Director

  • Jun OTANI
    Dr. Jun OTANI

    Vice-President for International Affairs

    Professor
    Faculty of Advanced Science and Technology
    Graduate School of Science and Technology

Distinguished Professors

  • Konstantinos KONTIS
    Dr. Konstantinos KONTIS

    Professor, Head of the Aerospace Sciences Division
    Sir Henry Mechan Chair of Engineering
    School of Engineering,
    University of Glasgow, UK

    Research Interests: Aerospace engineering
  • László PUSZTAI
    Dr. László PUSZTAI

    Scientific Advisor
    Wigner Research Centre for Physics,
    Hungarian Academy of Sciences, Hungary

    Research Interests: Structure of liquid and amorphous materials
  • Yufeng ZHENG
    Dr. Yufeng ZHENG

    Professor
    Department of Materials Science and Engineering,
    College of Engineering, Peking University, China

    Research Interests: Metallic biomaterials

Tenure-track Professor

  • Mitsuhiro AIDA
    Dr. Mitsuhiro AIDA
    Research Interests: Plant growth and development, morphogenesis, transcriptional regulation

    Plant growth and development is highly dependent on a small stem cell containing tissue called the shoot meristem, which is located at the tips of the plant body. The aim of our lab is to understand molecular and cellular mechanisms on how shoot meristems are formed, how organ formation from the meristems are controlled and how meristem activity is regulated upon various developmental and environmental cues, by using genetics, imaging techniques, biochemistry and genomics.

    スライド 1
    1.Mechanisms of shoot meristem formation

    We focus on a set of transcription factors named CUP-SHAPED COTYLEDON (CUC) 1, 2 and 3, whose activities are essential for shoot meristem formation in diverse developmental contexts. We are currently identifying and analyzing downstream genes of the CUC proteins and try to understand how the process of shoot meristem formation is regulated and coordinated.

    スライド 1
    2.Flower development and meristem activity

    The flower is a complex organ system specialized for reproduction and is formed from a modified meristem called the floral meristem. Through identifying factors responsible for floral meristem development, we try to uncover molecular and cellular mechanisms that govern flower formation.

    aida_GFP_PUCHI
    Technician Kazuko ONGA

Tenure-track Associate Professors

  • Takumi HIGAKI
    Dr. Takumi HIGAKI
    Research Interests: Quantitative bioimaging, cell morphogenesis, cytoskeleton and organelles
    Actin filaments of plants

    Actin, a protein that is ubiquitous in eukaryotes, forms actin filaments by its polymerization under physiological conditions. Actin filaments are deeply involved in cell morphological changes through formation of higher-order structures such as networks and bundles. In the case of plant cells in particular, actin filaments regulate various organelle dynamics. We aim for visible understanding of actin filament roles in cell division, cell expansion, and cell death, in which plant cell undergoes drastic changes.

    ImageJ=1.49v
    Stomatal development and movement

    The stomata on the plant leaf and stem surfaces is essential for plant survival because they are responsible for gaseous exchange and transpiration. The stomatal density and aperture is appropriately regulated in response to environmental cues. Using multiple approaches including biochemistry, molecular biology, live cell imaging, image analysis, and mathematical modeling, we aim for visible understanding of the multi-scale spatiotemporal control mechanism of plant stomata.

    ImageJ=1.49v
    Image analysis tool development

    When addressing problems in the cell biological studies described above, quantitative evaluations of cell structure and movement involving microscopic image analyses are essential. However, existing image analysis softwares are frequently insufficient. This is because the acquired image types and objectives are highly diversified in cell biology studies. For this reason, we are developing image analysis tools that would promote research progress from the standpoint of experimental cell biologists.

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    Technician Hitomi OKADA
  • Ruda LEE
    Dr. Ruda LEE
    Research Interests: Molecular engineering, molecular imaging, nanomedicine, and drug delivery

    Research in the Lee lab develop novel molecular imaging sensor and multi-drug delivery carrier for Theragnostics (Therapy + Diagnosis).

    1. Enzyme specific activated imaging sensor based real-time in vivo imaging

    Proteases are among the most studied enzyme families due to their involvement in the regulation of diverse disease processes and their potential value as biomarkers and therapeutic targets. We reported various protease target Near-infrared fluorescence (NIRF) imaging sensors and detecting pathologic processes at the cellular and molecular levels in vivo, such as cancer, arthritis, brain disorder and inflammation.

    lee_fig01
    2. Combination drug delivery using biocompatible polymer nanoconstructs

    Nanoconstructs can simultaneously deliver multiple agents to cancerous lesions enabling de facto combination therapies. We reported that multi-drug loaded nanoconstructs delivery to malignant mass show synergistic effect.

    lee_fig02
  • Atsushi SAINOKI
    Dr. Atsushi SAINOKI
    Research Interests: Sustainable energy development, underground hard rock mining, rock slope stability, and induced seismicity

Tenure-track Assistant Professor

  • Takashi ISHIDA
    Dr. Takashi ISHIDA
    Research Interests: Plant stem cell and development
    I. Analyses of peptide hormone mediated intercellular communications in shoot meristem.

    Coordinated cell proliferation and cell differentiation are essential processes in multicellular organisms. To achieve these functions, organisms have developed scrupulously designed cell-to-cell communication systems over the course of evolution. Plants have established unique ligand-receptor-based signaling modules, such as the CLAVATA (CLV) pathway, which comprises the CLV3 peptide hormone and the extracellular leucine-rich repeat (LRR) domain-containing receptors. In the shoot apical meristem (SAM) of Arabidopsis thaliana (Arabidopsis), CLV signal transducers and WUSCHEL (WUS), a homeobox transcription factor, form a negative feedback loop that controls the number of stem cells.
    Recently, I have showed that the Arabidopsis G protein beta-subunit1 (AGB1) is involved in the CLV signaling pathway. agb1 mutant exhibits an enlarged SAM and increased number of carpel, similar to that of clv mutants. We are aiming to elucidate further molecular insights of these proteins.
    Reference : Ishida et al., EMBO rep, 2014

    II. Exploring molecular machineries that regulate stem cell activities in root meristem.

    Coordination between cell proliferation and cell differentiation is important also in root meristem. Plants require the cell-to-cell communication system to regulate their activities and to ensure for precise postembryonic development. Shoot and root systems are thought to share common mechanism for carrying out this process; however, its molecular basis is largely unclear. It has been suggested that synthetic CLV3/ EMBRYO SURROUNDING REGION (CLE) peptide treatment shrank the root meristem through the CLV-related receptors in Arabidopsis.
    I have identified several molecules that are involved in the CLV-like signaling pathway in root, e.g. BAM1, RPK2 and PUB4. Mutation in these genes decreased sensitivity to the CLE-peptides. Further, we have found that several signaling factors are expressed in limited cells of the root meristem, suggesting that these cells may be responsible for the CLE peptide-stimulated shrinkage of root meristem. We are deciphering what types of cells are involved in the regulatory mechanisms in the root meristem.
    Reference : Kinoshita et al., Development, 2015; Shimizu et al., New phytol, 2015

    III. Phytoparasitic nematodes hijack vascular stem cells

    The developmental plasticity is one of the most striking features of plant morphogenesis, as plants are able to vary their shapes in response to environmental cues. Biotic or abiotic stimuli often promote organogenesis in plants that is not observed under normal growth conditions. Root-knot nematodes (RKNs) are known to parasitize multiple species of rooting plants and to induce characteristic tissue expansion called galls or root-knots (RKs), on the roots of their hosts by perturbing the plant cellular machinery. RKs contain giant cells (GCs) and neighboring cells (NCs), and the GCs are a source of nutrients for the parasitizing nematode. Highly activated cell proliferation was observed in galls. However, the underlying mechanisms that regulate the symptoms that are triggered by the plant-animal interaction have not yet been elucidated.
    We have established in vitro infection assay system with Meloidogyne incognita. By utilizing the in vitro system, we are trying to understand how the nematodes modulate developmental regulation mechanisms of plant cells to ensure the atypical cell proliferation and GC formation during the infection processes.
    Yamaguchi et al., Front Plant Sci, 2017

    Technician Mika YOSHIMURA

Postdoctoral Researchers

  • Minwoo KIM
    Dr. Minwoo KIM

    Lee Lab

    Research Interests: Theragnosis, polymers, liposomes, and biomimetic nanomedicine
  • Akiko NAKAMASU
    Dr. Akiko NAKAMASU

    Higaki Lab

    Research Interests: Pattern formation, plant morphogenesis, and theoretical and mathematical biology
  • Adam Karl SCHWARTZKOPFF
    Dr. Adam Karl SCHWARTZKOPFF

    Sainoki Lab

    Research Interests: Rock fracture mechanics, three-dimensional crack propagation prediction, analytical and numerical calculations of stress intensity factors, hydraulic fracturing, and rock failure analysis

Young Faculty Members for International Joint Research

  • Takahiro HOSONO
    Dr. Takahiro HOSONO

    Faculty of Advanced Science and Technology

    Research Interests: Environment dynamics analysis, Environmental assessment, Hydro-environmental science, Environmental isotope science, Natural disasters
  • Kei Ishida
    Dr. Kei Ishida

    Faculty of Advanced Science and Technology

    Research Interests: Hydrology
  • Makoto KUMON
    Dr. Makoto KUMON

    Robot, Control and Instrumentation Group, Division of Environmental Science, Faculty of Advanced Science and Technology

    Research Interests: Robotics, UAV, real time embedded systems, control applications, nonlinear systems
  • Mizue MUNEKATA
    Dr. Mizue MUNEKATA

    Advanced Thermal and Fluid Energy System Group, Division of Industrial Fundamentals, Faculty of Advanced Science and Technology

    Research Interests: Fluid engineering
  • Masayuki TANABE
    Dr. Masayuki TANABE

    Signal and Information Processing Group, Division of Environmental Science,
    Faculty of Advanced Science and Technology

    Research Interests: Ultrasound Imaging, Signal Processing

Visiting Professors

  • U Rajendra ACHARYA
    Dr. U Rajendra ACHARYA

    Senior faculty member
    Ngee Ann Polytechnic, Singapore

    Research Interests: Signal and Image processing and Artificial Intelligence
  • José E. ANDRADE
    Dr. José E. ANDRADE

    Professor
    California Institute of Technology (Caltech),USA

    Research Interests: Developing a fundamental understanding of the multiscaleand multiphysical behaviors of porous materials—everything from soils, rocks, and concrete to bone.
    Behavior of granular materials like sand, snow, and even grain stored in silos.
  • Josep-Lluís BARONA-VILAR
    Dr. Josep-Lluís BARONA-VILAR

    Professor
    Institute of History of Medicine and Science López Piñero (IHMC),
    University of Valencia, Spain

    Research Interests: History of science, history of medicine
  • Jorge Norberto BELTRAMINI
    Dr. Jorge Norberto BELTRAMINI

    Adjunct Professor-Catalysis for Clean Energy Group Leader
    Center for Tropical Crops & Bio-Commodities-Faculty of Science &Engineering
    The University of Queensland, Australia

    Research Interests: Catalysis, material science, energy
  • Paul BOWEN
    Dr. Paul BOWEN

    Professor
    School of Metallurgy and Materials
    University of Birmingham, UK

    Research Interests: Characterisation, development, fracture and fatigue of alloys and composite materials (MMCs and CMCs), etc. Please see below.
  • Pierre BREUL
    Dr. Pierre BREUL

    Professor
    University of Clermont Auvergne, France

    Research Interests: Soils and granular materials mechanics  
  • Maria Jose COCERO
    Dr. Maria Jose COCERO

    Professor
    Chemical Engineering & Environmental Technology
    The University of Valladolid, Spain

    Research Interests: Development of biorefinery processes and products.
    Healthy and high added value products from renewable raw materials.
    Intensification of processes through the implementation of new technologies for revaluation of raw materials and waste.
    Energy and fuels for the sustainable development.
  • Marc DE BOISSIEU
    Dr. Marc DE BOISSIEU

    Director
    SIMaP, CNRS, Université Grenoble Alpes, France

    Research Interests: Quasicrystals, structure, phonon and phason,
    Coherent x-ray diffraction imaging,
    Ge based clathrates
  • Patrice DELMAS
    Dr. Patrice DELMAS

    Associate Professor
    Department of Computer Science,
    The University of Auckland, New Zealand

    Research Interests: Image processing techniques applied to soil science, 2D/3D medical imaging, Theoretical and Applied Computer Vision at large
  • Martin DIENWIEBEL
    Dr. Martin DIENWIEBEL

    Heisenberg-Professor
    Applied Nanotribology
    Karlsruhe Institute for Technology (KIT), Germany

    Research Interests: Tribology, surface science, nanotribology
  • Martino DI SERIO
    Dr. Martino DI SERIO

    Professor
    University of Naples Federico II, Italy

    Research Interests: Catalysis, Green Chemistry
  • Derek ELSWORTH
    Dr. Derek ELSWORTH

    Professor
    Department of Energy and Mineral Engineering and of Geosciences
    The Pennsylvania State University, USA

    Research Interests: Computational mechanics, rock mechanics, and in the mechanical and transport characteristics of fractured rocks
  • Carolina ESCOBAR
    Dr. Carolina ESCOBAR

    Assistant Professor
    Department of Environmental Sciences
    School of Environmental Sciences and Biochemistry
    University of Castilla La Mancha, Spain

    Research Interests: Phytopathology (Molecular knowledge of the Plant-nematode interaction and nematodes control)
  • Amir A. FARAJIAN
    Dr. Amir A. FARAJIAN

    Associate Professor
    Department of Mechanical and Materials Engineering
    Wright State University, USA

    Research Interests: Nanoscience and nanotechnology with emphasis on computational modeling, sensors, materials for renewable energy, inelastic response, nano- and molecular-electronics, nanoelectromechanical systems, electronic and thermal quantum transports, bio-inspired nanomaterials.
  • Etsuko FUJITA
    Dr. Etsuko FUJITA

    Senior Chemist
    Chemistry Division,
    Brookhaven National Laboratory, USA

    Research Interests: Photochemistry of transition-metal complexes, organometallic compounds, and band-gap-narrowed semiconductors; photochemical and electrochemical COreduction and water splitting; small molecule activation
  • Tomonari FURUKAWA
    Dr. Tomonari FURUKAWA

    Professor
    Department of Mechanical Engineering
    Virginia Polytechnic Institute and State University, USA

    Research Interests: Robotics, autonomous systems, computational/experimental mechanics
  • Hamid GHANDEHARI
    Dr. Hamid GHANDEHARI

    Professor
    Director of Utah Center for Nanomedicine,
    Professor of Department of Pharmaceutics and Pharmaceutical Chemistry and Bioengineering,
    University of Utah, USA

    Research Interests: Engineering biomaterials for delivery of bioactive agents, toxicology of engineered nanoconstructs
  • Olivier HAMANT
    Dr. Olivier HAMANT

    Research Director
    INRA, RDP, ENS Lyon, France

    Research Interests: Plant development, mechanical signals
  • Christian HARDTKE
    Dr. Christian HARDTKE

    Professor
    Department of Plant Molecular Biology, University of Lausanne, Switzerland

    Research Interests: Plant development, vascular differentiation, plant hormones, peptide signalling
  • Jens HARTMANN
    Dr. Jens HARTMANN

    Professor
    Institute for Geology, Universität Hamburg, Germany

    Research Interests: Aquatic geochemistry, global biogeochemical cycles
  • Yang KIM
    Dr. Yang KIM

    Professor
    Kosin University, Korea

    Research Interests: Supramolecular chemistry, chemosensor
  • Alexei KUZMIN
    Dr. Alexei KUZMIN

    Head of Laboratory
    Laboratory of Materials Morphology and Structure Investigations
    Institute of Solid State Physics, University of Latvia, Riga, Latvia

    Research Interests: X-ray absorption spectroscopy, computer simulations, oxide materials
  • Ick Chan KWON
    Dr. Ick Chan KWON

    Presidential Scholar
    Department of Cancer Biology, Dana Farber Cancer Institute, Harvard Medical School, USA

    Principal Research Scientist
    Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Korea

    Research Interests: Drug delivery system, molecular imaging, theragnosis, nanomedicine
  • Pavel LEJČEK
    Dr. Pavel LEJČEK

    Professor
    Institute of Physics, Academy of Sciences of the Czech Republic, Czech Republic, AND
    University of Chemistry and Technology, Prague, Czech Republic

    Research Interests: Metallurgy, materials science
  • Viren Ivor MENEZES
    Dr. Viren Ivor MENEZES

    Professor
    Department of Aerospace Engineering,
    Indian Institute of Technology Bombay, India

    Research Interests: Applications of shock waves and hypersonic aerothermodynamics
  • Matthieu MICOULAUT
    Dr. Matthieu MICOULAUT

    Professor
    Sorbonne University, France

    Research Interests: Glasses, liquids.
    Glass transition, structure of disordered materials.  
  • Dmitri Aleks MOLODOV
    Dr. Dmitri Aleks MOLODOV

    Professor
    Institute of Physical Metallurgy and Metal Physics,
    RWTH Aachen University, Germany

    Research Interests: Characterization and control of micro-structure evolution in polycrystalline solids; Dynamic properties of interfaces in metals and alloys; Crystal plasticity
  • Rahul Raveendran NAIR
    Dr. Rahul Raveendran NAIR

    Professor
    Materials Physics
    National Graphene Institute and School of Chemical Engineering and Analytical Science
    The University of Manchester, UK

    Research Interests: Materials physics, 2D materials, nanoscience and nanotechnology, 2D materials based membranes and coating, nanofluidics
  • Reiko ODA
    Dr. Reiko ODA

    Research Director
    CBMN UMR5248, CNRS,
    University of Bordeaux, France

    Research Interests: Colloid/surfactant chemistry, physical chemistry
  • Ramesh Shanmughom PILLAI
    Dr. Ramesh Shanmughom PILLAI

    Professor
    Department of Molecular Biology,
    University of Geneva, Switzerland

    Research Interests: RNA biology and epigenetics
  • Zoran REN
    Dr. Zoran REN

    Professor
    Faculty of Mechanical Engineering,
    University of Maribor, Slovenia

    Research Interests: Advanced computation solid mechanics, cellular materials, impact and dynamics
  • Christian RENTENBERGER
    Dr. Christian RENTENBERGER

    Associate Professor
    Faculty of Physics
    University of Vienna, Austria

    Research Interests: Structure and properties of nanocrystalline and amorphous materials, electron microscopy methods
  • Shirley SHEN
    Dr. Shirley SHEN

    Principal Research Scientist
    Commonwealth Scientific and Industrial Research Organisation (CSIRO), Australia

    Research Interests: Nanomaterials, Surfacel interphase designs and embedded functions
  • Gioacchino (Cino) VIGGIANI
    Dr. Gioacchino (Cino) VIGGIANI

    Professor
    Solid Mechanics and Civil Engineering
    Université Grenoble Alpes, France

    Research Interests: Geomechanics
  • Thomas WAITZ
    Dr. Thomas WAITZ

    Associate University Professor
    Faculty of Physics, University of Vienna, Austria

    Research Interests: Nanostructured materials, shape memory alloys, phase transformations, transmission electron microscopy
  • Andrew WHITTLE
    Dr. Andrew WHITTLE

    Professor of Civil & Environmental Engineering
    Massachusetts Institute of Technology (MIT), USA

    Research Interests: Geotechnical, urban infrastructure    
  • Zhenghe XU
    Dr. Zhenghe XU

    Dean
    College of Engineering,
    Southern University of Science and Technology, Shenzhen, China

    Teck Professor
    Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Canada

    Research Interests: Engineering of nano particles and composites for bio, energy and environmental applications, etc.
  • Firuz ZARE
    Dr. Firuz ZARE

    Professor
    Power and Energy Group,
    The University of Queensland, Australia

    Research Interests: Power electronics and energy conversion

Administrative Staff

Chief Junichi KUMAGAI
Senior Administrator Tomomi MAEDA
Staff Member Kenichi FUKUDA
Staff Member Tae SATO
University Research Administrator (URA) Chikako UEDA
International Coordinator Shoko MURAO
Clerical Assistant Junko ODAWARA
Clerical Assistant Shiho ISHII