STAFF

Director

  • Kazuki TAKASHIMA
    Dr. Kazuki TAKASHIMA

    Distinguished Professor

    International Research Organization for Advanced Science and Technology

Vice Director

  • Kei TODA
    Dr. Kei TODA

    Professor

    Faculty of Advanced Science and Technology

Distinguished Professors

  • Jorge Norberto BELTRAMINI
    Dr. Jorge Norberto BELTRAMINI

    Adjunct Professor-Catalysis for Clean Energy Group Leader
    Center for Tropical Crops & Bio-Commodities-Faculty of Science &Engineering
    Queensland University of Technology (QUT), Australia

    Research Interests: Catalysis, material science, energy
  • Konstantinos KONTIS
    Dr. Konstantinos KONTIS

    Professor, Head of the Aerospace Sciences Division
    Sir Henry Mechan Chair of Engineering
    School of Engineering,
    University of Glasgow, UK

    Research Interests: Aerospace engineering
  • László PUSZTAI
    Dr. László PUSZTAI

    Scientific Advisor
    Wigner Research Centre for Physics
    Hungary

    Research Interests: Structure of liquid and amorphous materials
  • Yufeng ZHENG
    Dr. Yufeng ZHENG

    Professor
    Department of Materials Science and Engineering,
    College of Engineering, Peking University, China

    Research Interests: Metallic biomaterials

Tenure-track Professor

  • Mitsuhiro AIDA
    Dr. Mitsuhiro AIDA
    Research Interests: Plant growth and development, morphogenesis, transcriptional regulation

    Plant growth and development is highly dependent on a small stem cell containing tissue called the shoot meristem, which is located at the tips of the plant body. The aim of our lab is to understand molecular and cellular mechanisms on how shoot meristems are formed, how organ formation from the meristems are controlled and how meristem activity is regulated upon various developmental and environmental cues, by using genetics, imaging techniques, biochemistry and genomics.

    スライド 1
    1.Mechanisms of shoot meristem formation

    We focus on a set of transcription factors named CUP-SHAPED COTYLEDON (CUC) 1, 2 and 3, whose activities are essential for shoot meristem formation in diverse developmental contexts. We are currently identifying and analyzing downstream genes of the CUC proteins and try to understand how the process of shoot meristem formation is regulated and coordinated.

    スライド 1
    2.Flower development and meristem activity

    The flower is a complex organ system specialized for reproduction and is formed from a modified meristem called the floral meristem. Through identifying factors responsible for floral meristem development, we try to uncover molecular and cellular mechanisms that govern flower formation.

    aida_GFP_PUCHI
    Technician Kazuko ONGA

Tenure-track Associate Professors

  • Takumi HIGAKI
    Dr. Takumi HIGAKI
    Research Interests: Quantitative bioimaging, cell morphogenesis, cytoskeleton and organelles
    Actin filaments of plants

    Actin, a protein that is ubiquitous in eukaryotes, forms actin filaments by its polymerization under physiological conditions. Actin filaments are deeply involved in cell morphological changes through formation of higher-order structures such as networks and bundles. In the case of plant cells in particular, actin filaments regulate various organelle dynamics. We aim for visible understanding of actin filament roles in cell division, cell expansion, and cell death, in which plant cell undergoes drastic changes.

    ImageJ=1.49v
    Stomatal development and movement

    The stomata on the plant leaf and stem surfaces is essential for plant survival because they are responsible for gaseous exchange and transpiration. The stomatal density and aperture is appropriately regulated in response to environmental cues. Using multiple approaches including biochemistry, molecular biology, live cell imaging, image analysis, and mathematical modeling, we aim for visible understanding of the multi-scale spatiotemporal control mechanism of plant stomata.

    ImageJ=1.49v
    Image analysis tool development

    When addressing problems in the cell biological studies described above, quantitative evaluations of cell structure and movement involving microscopic image analyses are essential. However, existing image analysis softwares are frequently insufficient. This is because the acquired image types and objectives are highly diversified in cell biology studies. For this reason, we are developing image analysis tools that would promote research progress from the standpoint of experimental cell biologists.

    ImageJ=1.49v
    Technician Remi KAWAKAMI
    Technician Hitomi OKADA
  • Ruda LEE
    Dr. Ruda LEE
    Research Interests: Molecular engineering, molecular imaging, nanomedicine, and drug delivery
    Prof. Ruda Lee, PH.D.
    Associate Professor
    International Research Organization for Advanced Science and Technology (IROAST)
    Kumamoto University, Japan

    Professional Education

    Ph.D., Korea University, School of Medicine (2013)

    Research Training

    2017-present Associate Professor (Kumamoto University, Japan)
    2014-2016 Postdoctral fellow (IIT, Italy)
    2013-2014 Postdoctral fellow (KIST, Korea)
    2009-2013 MS & Ph.D course trainee (KIST, Korea)
    2008-2009 Research Assistant (KIST, Korea)

    Selected peer-reviewed publications

    1. Lee A et al. Early diagnosis of arthritis in mice with collagen-induced arthritis, using a fluorogenic MMP 3-specific polymeric probe. Arthritis Rheum 2011
    2. Lee A et al. Measurement of MMP Activity in Synovial Fluid in Cases of Osteoarthritis and Acute Inflammatory Conditions of the Knee Joints Using a Fluorogenic Peptide Probe-Immobilized Diagnostic Kit. Theranostics 2012
    3. Lee A et al. A novel near-infrared fluorescence chemosensor for copper ion detection using click ligation and energy transfer. Chem Comm. 2013
    4. Lee A et al. TNF-α Gene Silencing Using Polymerized siRNA/Thiolated Glycol Chitosan Nanoparticles for Rheumatoid Arthritis. Mol Ther 2014
    5. Lee A et al. Spherical Polymeric Nanoconstructs for Combined Chemotherapeutic and anti-Inflammatory Therapies. Nanomedicine : NBM 2016
    6. Lee A et al. Dexamethasone-loaded nanoconstructs for treating and monitoring inflammation in murine colitis models. Theranostics 2017
    7. Lee A et al. Visualization of MMP-2 Activity Using Dual-Probe Nanoparticles to Detect Potential Metastatic Cancer Cells. Nanomaterials 2018
    8. Kim MW et al. Anti-EGF Receptor Aptamer-Guided Co-Delivery of Anti-Cancer siRNAs and Quantum Dots for Theranostics of Triple-Negative Breast Cancer. Theranostics 2019 (co-author)
    9. Ueno S et al. Development of ErbB2-Targeting Liposomes for Enhancing Drug Delivery to ErbB2-Positive Breast Cancer. Pharmaceutics 2020 (Corresponding)
    10. Park YI et al. pH-sensitive multi-drug liposomes targeting folate receptor β for efficient treatment of non-small cell lung cancer.Journal of Controlled Release 2021 (Corresponding)

    Research interest

    Research in the Lee lab develops novel molecular imaging sensors and multifunction drug delivery carriers for ‘Theragnosis’ (Therapy + Diagnosis).

    1. Enzyme specific activated imaging sensor based real-time in vivo imaging

    Proteases are among the most studied enzyme families due to their involvement in the regulation of diverse disease processes and their potential value as biomarkers and therapeutic targets. We reported various protease target Near-infrared fluorescence (NIRF) imaging sensors and detecting pathologic processes at the cellular and molecular levels in vivo, such as cancer, arthritis, brain disorder and inflammation.

    lee_fig01

    2. Active targeting drug delivery nanomaterials

    Active targeted drug delivery material delivers a therapeutic and/or diagnostic agent to a targeted diseased area. Drug-loaded nanomaterials (NPs) are decorated by the peptide, aptamer, antibody for recognition by specific receptors/antigens on target cells. In this strategy, NPs can avoid non-specific biodistribution, reducing cytotoxicity and treatment dosage. It could provide patients to have chances of effective therapeutic treatment.

    3. Stimuli responsive controlled drug release system

    Owing to precise stimuli response, stimuli-responsive DDSs can control drug release, so as to improve the curative effects, reduce the damage of normal tissues and organs, and decrease the side effects of traditional anticancer drugs. We designed endogenous stimuli-responsive materials (pH, enzyme and redox responsive) and exogenous stimuli-responsive materials (such as light and ultrasound).

    Lab members
    -  Associate Prof. Ruda Lee
    -  Students M2 Sho Ueno
    M1 Naoki Furutachi
    M1 Sho Tanigawa
    B4 Miu Goto
    B4 Nozomi Koga

  • Hiroki MATSUO
    Dr. Hiroki MATSUO
    Research Interests: Ferroelectrics, Lattice defects, Domain engineering,  Pulsed-laser
    deposition

    ・Research interest

    Ferroelectric materials have spontaneous electric polarization arising from a non-centrosymmetric crystal structure that can reversed by application of external electric field. Because of their characteristic polar structure, ferroelectric materials exhibit various functions such as piezoelectricity, pyroelectricity, electro-optic effect and anomalous photovoltaic effect, etc. Current research interest is the exploration of novel functions of the ferroelectric materials based on the following materials design strategies.

    1.Ferroelectric artificial superlattice

    A superlattice thin film has a periodic structure composed of thin layers of two or more materials. Because of an interfacial effect and a strong interaction between the layers, the superlattice sometimes exhibits unexpected property that is not predictable from the bulk properties of the constituting materials. The study aims to develop a ferroelectric thin-film capacitor that exhibits quite high energy density by exploiting the characteristic feature of the superlattice structure. For the fabrication of the ferroelectric superlattice, pulsed-laser deposition method with a reflection high energy electron diffraction system is used.

    2.Ferroelectric photovoltaic effect

    Ferroelectric materials exhibit characteristic photovoltaic responses owing to their polar crystal structure. While photovoltage generated by the conventional p-n junction of semiconductors is limited by bandgap energy of the materials, ferroelectric materials exhibit a high photovoltage exceeding the bandgap energy of them. We aim to enhance the photovoltaic response of the ferroelectric materials especially under visible light irradiation by chemical doping and by controlling ferroelectric domain structures.

    3.Interaction between ferroelectric polarization and lattice defects

    Charged lattice defects in the ferroelectric crystals strongly interact with the ferroelectric polarization through electrostatic and mechanical effects. The interaction enables control of the ferroelectric property by designing species, concentration, and distribution of the defects in the crystals. The goal of this study is to establish an effective approach to obtain desired ferroelectric properties by defect engineering.

Tenure-track Assistant Professor

None for now

Project Assistant Professor

  • Akiko NAKAMASU
    Dr. Akiko NAKAMASU

    Higaki Lab

    Research Interests: Pattern formation, plant morphogenesis, and theoretical and mathematical biology

Postdoctoral Researchers

  • Mizuki YAMADA
    Dr. Mizuki YAMADA

    Aida Lab

    Research Interests: Plant morphogenesis, plant signaling

Young Faculty Members for International Joint Research

  • Takahiro HOSONO
    Dr. Takahiro HOSONO

    Faculty of Advanced Science and Technology

    Research Interests: Environment dynamics analysis, Environmental assessment, Hydro-environmental science, Environmental isotope science, Natural disasters
  • Kei Ishida
    Dr. Kei Ishida

    Center for Water Cycle, Marine Environment and Disaster Management

    Research Interests: Hydrology
  • Mizue MUNEKATA
    Dr. Mizue MUNEKATA

    Advanced Thermal and Fluid Energy System Group, Division of Industrial Fundamentals, Faculty of Advanced Science and Technology

    Research Interests: Fluid engineering
  • Yuta NAKASHIMA
    Dr. Yuta NAKASHIMA

    Faculty of Advanced Science and Technology

    Research Interests: Biomedical engineering, Biomedical devices

Visiting Professors

  • U Rajendra ACHARYA
    Dr. U Rajendra ACHARYA

    Senior faculty member
    Ngee Ann Polytechnic, Singapore

    Research Interests: Signal and Image processing and Artificial Intelligence
  • José E. ANDRADE
    Dr. José E. ANDRADE

    Professor
    California Institute of Technology (Caltech),USA

    Research Interests: Developing a fundamental understanding of the multiscaleand multiphysical behaviors of porous materials—everything from soils, rocks, and concrete to bone.
    Behavior of granular materials like sand, snow, and even grain stored in silos.
  • Josep-Lluís BARONA-VILAR
    Dr. Josep-Lluís BARONA-VILAR

    Professor
    Institute of History of Medicine and Science López Piñero (IHMC),
    University of Valencia, Spain

    Research Interests: History of science, history of medicine
  • Pouyan BOUKANY
    Dr. Pouyan BOUKANY

    Associate Professor
    Delft University of Technology,
    Netherlands

    Research Interests: Living Soft Matter, complex fluids, biomicrofluidics and biomechanics
  • Olivier BOUTIN
    Dr. Olivier BOUTIN

    Professor Deputy Director M2P2, Director Master Chemical Engineering
    M2P2 Laboratory, Aix Marseille University, France

    Research Interests: Chemical engineering, high pressure and high temperature process for waste treatment and biomass valorisation, Wet air oxidation.
  • Paul BOWEN
    Dr. Paul BOWEN

    Professor
    School of Metallurgy and Materials
    University of Birmingham, UK

    Research Interests: Characterisation, development, fracture and fatigue of alloys and composite materials (MMCs and CMCs), etc. Please see below.
  • Pierre BREUL
    Dr. Pierre BREUL

    Professor
    University of Clermont Auvergne, France

    Research Interests: Soils and granular materials mechanics  
  • Maria Jose COCERO
    Dr. Maria Jose COCERO

    Professor
    Chemical Engineering & Environmental Technology
    The University of Valladolid, Spain

    Research Interests: Development of biorefinery processes and products.
    Healthy and high added value products from renewable raw materials.
    Intensification of processes through the implementation of new technologies for revaluation of raw materials and waste.
    Energy and fuels for the sustainable development.
  • Marc DE BOISSIEU
    Dr. Marc DE BOISSIEU

    Director
    SIMaP, CNRS, Université Grenoble Alpes, France

    Research Interests: Quasicrystals, structure, phonon and phason,
    Coherent x-ray diffraction imaging,
    Ge based clathrates
  • Patrice DELMAS
    Dr. Patrice DELMAS

    Associate Professor
    Department of Computer Science,
    The University of Auckland, New Zealand

    Research Interests: Image processing techniques applied to soil science, 2D/3D medical imaging, Theoretical and Applied Computer Vision at large
  • Martin DIENWIEBEL
    Dr. Martin DIENWIEBEL

    Heisenberg-Professor
    Applied Nanotribology
    Karlsruhe Institute for Technology (KIT), Germany

    Research Interests: Tribology, surface science, nanotribology
  • Martino DI SERIO
    Dr. Martino DI SERIO

    Professor
    University of Naples Federico II, Italy

    Research Interests: Catalysis, Green Chemistry
  • Derek ELSWORTH
    Dr. Derek ELSWORTH

    Professor
    Department of Energy and Mineral Engineering and of Geosciences
    The Pennsylvania State University, USA

    Research Interests: Computational mechanics, rock mechanics, and in the mechanical and transport characteristics of fractured rocks
  • Carolina ESCOBAR
    Dr. Carolina ESCOBAR

    Assistant Professor
    Department of Environmental Sciences
    School of Environmental Sciences and Biochemistry
    University of Castilla La Mancha, Spain

    Research Interests: Phytopathology (Molecular knowledge of the Plant-nematode interaction and nematodes control)
  • Amir A. FARAJIAN
    Dr. Amir A. FARAJIAN

    Professor
    Department of Mechanical and Materials Engineering
    Wright State University, USA

    Research Interests: Nanoscience and nanotechnology with emphasis on computational modeling, sensors, materials for renewable energy, inelastic response, nano- and molecular-electronics, nanoelectromechanical systems, electronic and thermal quantum transports, bio-inspired nanomaterials.
  • Etsuko FUJITA
    Dr. Etsuko FUJITA

    Senior Chemist
    Chemistry Division,
    Brookhaven National Laboratory, USA

    Research Interests: Photochemistry of transition-metal complexes, organometallic compounds, and band-gap-narrowed semiconductors; photochemical and electrochemical COreduction and water splitting; small molecule activation
  • Tomonari FURUKAWA
    Dr. Tomonari FURUKAWA

    Professor
    Department of Mechanical and Aerospace Engineering
    University of Virginia, USA

    Research Interests: Robotics, autonomous systems, computational/experimental mechanics
  • Hamid GHANDEHARI
    Dr. Hamid GHANDEHARI

    Professor
    Director of Utah Center for Nanomedicine,
    Professor of Department of Pharmaceutics and Pharmaceutical Chemistry and Bioengineering,
    University of Utah, USA

    Research Interests: Engineering biomaterials for delivery of bioactive agents, toxicology of engineered nanoconstructs
  • Olivier HAMANT
    Dr. Olivier HAMANT

    Research Director
    INRA, RDP, ENS Lyon, France

    Research Interests: Plant development, mechanical signals
  • Christian HARDTKE
    Dr. Christian HARDTKE

    Professor
    Department of Plant Molecular Biology, University of Lausanne, Switzerland

    Research Interests: Plant development, vascular differentiation, plant hormones, peptide signalling
  • Jens HARTMANN
    Dr. Jens HARTMANN

    Professor
    Institute for Geology, Universität Hamburg, Germany

    Research Interests: Aquatic geochemistry, global biogeochemical cycles
  • Yuichiro HIMEDA
    Dr. Yuichiro HIMEDA

    Prime Senior Researcher
    Carbon-based Energy Carrier Research Team, Global Zero Emission Research Center, National Institute of Advanced Industrial Science and Technology, Japan

    Research Interests: CO2 utilization, Homogeneous catalyst, Hydrogen carrier
  • Dragos HORVATH
    Dr. Dragos HORVATH

    CNRS Research Director
    Laboratory of Chemoinformatics UMR7140
    University of Strasbourg, France

     

    Research Interests: Chemoinformatics, Computer-aided Drug Design, Molecular Modeling, Implicit Solvent Models, Nature-Inspired Optimization Heuristics
  • Yang KIM
    Dr. Yang KIM

    Professor
    Kosin University, Korea

    Research Interests: Supramolecular chemistry, chemosensor
  • Alexei KUZMIN
    Dr. Alexei KUZMIN

    Head of Laboratory
    EXAFS Spectroscopy Laboratory
    Institute of Solid State Physics, University of Latvia, Riga, Latvia

    Research Interests: X-ray absorption spectroscopy, computer simulations, oxide materials
  • Ick Chan KWON
    Dr. Ick Chan KWON

    Presidential Scholar
    Department of Cancer Biology, Dana Farber Cancer Institute, Harvard Medical School, USA

    Principal Research Scientist
    Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Korea

    Research Interests: Drug delivery system, molecular imaging, theragnosis, nanomedicine
  • Youn-Woo LEE
    Dr. Youn-Woo LEE

    Professor
    School of Chemical and Biological Engineering,
    Seoul National University, Korea

    Research Interests: Supercritical Fluid Technology
  • Pavel LEJČEK
    Dr. Pavel LEJČEK

    Professor
    Institute of Physics, Academy of Sciences of the Czech Republic, Czech Republic, AND
    University of Chemistry and Technology, Prague, Czech Republic

    Research Interests: Metallurgy, materials science
  • Viren Ivor MENEZES
    Dr. Viren Ivor MENEZES

    Professor
    Department of Aerospace Engineering,
    Indian Institute of Technology Bombay, India

    Research Interests: Applications of shock waves and hypersonic aerothermodynamics
  • Matthieu MICOULAUT
    Dr. Matthieu MICOULAUT

    Professor
    Sorbonne University, France

    Research Interests: Glasses, liquids.
    Glass transition, structure of disordered materials.  
  • Dmitri Aleks MOLODOV
    Dr. Dmitri Aleks MOLODOV

    Professor
    Institute of Physical Metallurgy and Metal Physics,
    RWTH Aachen University, Germany

    Research Interests: Characterization and control of micro-structure evolution in polycrystalline solids; Dynamic properties of interfaces in metals and alloys; Crystal plasticity
  • Rahul Raveendran NAIR
    Dr. Rahul Raveendran NAIR

    Professor
    Materials Physics
    National Graphene Institute and School of Chemical Engineering and Analytical Science
    The University of Manchester, UK

    Research Interests: Materials physics, 2D materials, nanoscience and nanotechnology, 2D materials based membranes and coating, nanofluidics
  • Reiko ODA
    Dr. Reiko ODA

    Research Director
    CBMN UMR5248, CNRS,
    University of Bordeaux, France

    Research Interests: Colloid/surfactant chemistry, physical chemistry
  • Shie-Ming PENG
    Dr. Shie-Ming PENG

    Distinguished Research Professor
    National Taiwan University, Taiwan

    Research Interests: Inorganic Chemistry; Crystallography; Nano Science.
    Structure and Bonding of Transition Metal Complexes; Metal-Metal Bonds; Molecular Metal Wires; Molecular Electronics.
  • Ramesh Shanmughom PILLAI
    Dr. Ramesh Shanmughom PILLAI

    Professor
    Department of Molecular Biology,
    University of Geneva, Switzerland

    Research Interests: RNA biology and epigenetics
  • Zoran REN
    Dr. Zoran REN

    Professor
    Faculty of Mechanical Engineering,
    University of Maribor, Slovenia

    Research Interests: Advanced computation solid mechanics, cellular materials, impact and dynamics
  • Christian RENTENBERGER
    Dr. Christian RENTENBERGER

    Associate Professor
    Faculty of Physics
    University of Vienna, Austria

    Research Interests: Structure and properties of nanocrystalline and amorphous materials, electron microscopy methods
  • Stelios RIGOPOULOS
    Dr. Stelios RIGOPOULOS

    Reader in Thermofluids
    Department of Mechanical Engineering
    Imperial College London, UK

    Research Interests: Population balance modelling, aerosol science,  fluid mechanics, reacting flows, LES/DNS, PDF methods, combustion, crystallisation, chemical kinetics, machine learning.
  • Shirley SHEN
    Dr. Shirley SHEN

    Principal Research Scientist
    Commonwealth Scientific and Industrial Research Organisation (CSIRO), Australia

    Research Interests: Nanomaterials, Surfacel interphase designs and embedded functions
  • Atsushi URAKAWA
    Dr. Atsushi URAKAWA

    Professor
    Delft University of Technology (TU Delft), the Netherlands

    Research Interests: Heterogeneous catalysis, in situ / operando spectroscop
  • Gioacchino (Cino) VIGGIANI
    Dr. Gioacchino (Cino) VIGGIANI

    Professor
    Solid Mechanics and Civil Engineering
    Université Grenoble Alpes, France

    Research Interests: Geomechanics
  • Thomas WAITZ
    Dr. Thomas WAITZ

    Associate University Professor
    Faculty of Physics, University of Vienna, Austria

    Research Interests: Nanostructured materials, shape memory alloys, phase transformations, transmission electron microscopy
  • Andrew WHITTLE
    Dr. Andrew WHITTLE

    Professor of Civil & Environmental Engineering
    Massachusetts Institute of Technology (MIT), USA

    Research Interests: Geotechnical, urban infrastructure    
  • Zhenghe XU
    Dr. Zhenghe XU

    Dean
    College of Engineering,
    Southern University of Science and Technology, Shenzhen, China

    Teck Professor
    Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Canada

    Research Interests: Engineering of nano particles and composites for bio, energy and environmental applications, etc.
  • Firuz ZARE
    Dr. Firuz ZARE

    Professor
    Power and Energy Group,
    The University of Queensland, Australia

    Research Interests: Power electronics and energy conversion

Visiting Associate Professors

  • Tomoyasu MANI
    Dr. Tomoyasu MANI

    Assistant Professor
    Department of Chemistry, University of Connecticut, USA

    Research Interests: Electron and energy transfer, spin chemistry
  • Daniel P. ZITTERBART
    Dr. Daniel P. ZITTERBART

    Assistant Scientist
    Woods Hole Oceanographic Institution
    USA

    Research Interests: Marine Animal Remote Sensing

Administrative Staff

Chief Miyuki MIYAYAMA
Senior Administrator Tomomi MAEDA
Staff Member Takayuki UENO
Research Support Associate Tae SATO
Clerical Assistant Akiko TAJIRI
International Coordinator Junko MOTOORI